A performance comparison of nine selected liquid scintillation cocktails.
نویسندگان
چکیده
Sample load capacity, sample compatibility, influence of sample load on (3)H/(14)C counting efficiency, background count rate, figure of merit, quench resistance, and sample stability for nine selected, commercially available, liquid scintillation cocktails are presented in this study. The cocktails tested are Ecoscint A, Insta-Gel Plus, OptiPhase Hisafe 3, OptiPhase Trisafe, Ready Gel, SafeScint 1:1, Ultima Gold, Ultima Gold LLT, and Ultima Gold XR. For the data acquisition a Packard TriCarb Model 1900CA and a Quantulus 1220 liquid scintillation counter is used. All samples are prepared in either 20mL low potassium, borosilicate glass vials or 20mL high density, polyethylene vials. The aim of the full comparison study is to determine a single cocktail that best suits all measurement requirements of the liquid scintillation laboratory at SCK.CEN for the determination of low levels of radioactivity in biological and environmental samples. The results published in this report are intended to help other laboratories in selecting a cocktail fit for their purposes or to set up a similar study.
منابع مشابه
Comparison of the efficacy of biodegradable and non-biodegradable scintillation liquids on the counting of tritium- and [14C]-labeled compounds.
The widespread use of H and 14C in research has generated a large volume of waste mixed with scintillation liquid, requiring an effective control and appropriate storage of liquid radioactive waste. In the present study, we compared the efficacy of three commercially available scintillation liquids, Optiphase HiSafe 3, Ultima-Gold AB (biodegradable) and Insta-Gel-XF (non-biodegradable), in term...
متن کاملCocktails for Liquid Scintillation Counting
It is most important to assure 4 π−geometry in liquid scintillation counting for accurate results1. Usually this can be assured by dissolution of the sample in an appropriate cocktail. The cocktail does not only contain a solvent but also at least one scintillator and surfactants for aqueous samples because aqueous samples are completely insoluble in the pure organic solvents and scintillators....
متن کاملSafer Flow Cocktails
The use and detection of radiotracers in organic and biological chemistry has benefitted from advances in the efficiency and sophistication of both the chromatographic and the radioactive detection techniques. As a result, the chromatographic separation of radiolabeled compounds, sometimes referred to as “radiochromatography,” is now carried out in many laboratories throughout the world. The ba...
متن کاملDetermination of chemical and radiochemical purity of [14C] clozapine by high performance liquid chromatography and liquid scintillation [Persian]
Introduction: The mechanism of action and metabolism of clozapine, a complex drug used in psychopharmacology, is not completely understood. The effects of this compound in human body are related to some interactions with serotonin and dopamine neurotransmitter receptors. To further elucidate the mechanism of action and to support ongoing drug metabolism studies, [14C] clozapine with suita...
متن کاملThe Effect of Quench on Quantitating Alpha Radionuclides by Liquid Scintillation Counting
Detecting and quantitating alpha emitting radionuclides are routine tasks in nuclear energy and environmental monitoring. For this purpose, liquid scintillation counting (LSC) is an excellent method because alphas are counted with nearly 100% counting efficiency with low backgrounds, even with severe quenching. Quenching agents such as inorganic acids, organic acids, and extractive scintillator...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine
دوره 66 6-7 شماره
صفحات -
تاریخ انتشار 2008